Author | Area, subjects | Study design | HPV test | HPV prevalence for any and specific genotypes among all tested womena | Comments |
---|---|---|---|---|---|
Schmauz et al., 1989 [55] | Mulago hospital, cervical tissues from 34 cases and 23 controls | Case Control | Southern Blot analysis | Casesa HPV 16/18, 50% HPV 16, 15% HPV 18, 35% Controlsa HPV 18, 4.4% | Prevalence of HIV a Cases, 5.9% Controls, 21.7% Odds of cervical cancer HPV 18 (OR* = 12.0) HPV16/18 (OR* = 22.0) |
Odida et al., 2008 [56] | Mulago, Pathology Department 186 paraffin embedded histologically confirmed archival cervical cancer cases Collected 1968-69, 1970-79, and 1980-89. | Case series | SPF10/LIPA | Any HPVa, 61.3% Type-specific genotypes a HPV 16/18, 73.5% HPV 16, 44.7% HPV 18, 28.8% HPV 45, 9.6% | Types 146 Squamous cell carcinoma 35 adenocarcinoma 3 Adenosquamous 2 undifferentiated types |
Odida et al., 2010 [57] | Mulago Hospital, Kampala, 171 pairs of paraffin embedded and freshly frozen tissue samples collected between September 2004 and December 2006 | Case series | SPF10/LIPA | Any HPVa, Frozen tissue, 90.1% Type-specific genotypes a HPV 16, 47.4% HPV 18, 19.5% HPV 45, 9.7% HPV 51, 1.9% HPV 52, 1.3% Any HPVa, Paraffin embedded tissue, 88.9% Type-specific genotypes a HPV 16, 47.4% HPV 18, 23.7% HPV 45, 7.9% HPV 51, 1.3% HPV 52, 1.3% | Multiple HPV genotypesa Frozen tissue, 7.1% Paraffin embedded, 4.6% Single HPV genotypesa Frozen tissue, 92.9% (95% CI†: 87.6-96.4) Paraffin embedded, 94.7% (95% CI†: 89.9-97.7) |