Infectious Agents and Cancer

Table 5 Results of p16 expression by HPV results

From: Comparison of human papillomavirus detection between freshly frozen tissue and paraffin embedded tissue of invasive cervical cancer

HPV results fresh/paraffin preservation	p16
	-		++		+++		Total
	N	%	N	%	N	%	N	%
Concordant HPV negative	1^a	16.7	1^b	16.7	4^e	66.7	6	100
Concordant HPV positive	0	0.0	1^c	6.7	14^f	93.3	15	100
Fresh HPV positive, Paraffin HPV negative	0	0.0	0	0.0	9^g	100	9	100
Fresh HPV negative, Paraffin HPV positive	0	0.0	2^d	20	8^h	80	10	100
Total	1	2.5	4	10	35	87.5	40	100

p16-: < 5% stained cells; p16++: 26-75%; p16+++: > 75%
Histologies:
^a adenocarcinoma NOS (not other specified)
^b undifferentiated carcinoma
^c undifferentiated carcinoma
^d 1 adenocaricnoma and 1 undifferentiated carcinoma
^e 4 squamous cell carcinoma
^f 13 squamous cell carcinoma and 1 undifferentiated carcinoma
^g 5 squamous cell carcinoma, 1 adenocarcinoma and 3 undifferentiated carcinoma
^h 7 squamous cell carcinoma, 1 adenocarcinoma

Back to article page

ISSN: 1750-9378

Contact us

General enquiries: journalsubmissions@springernature.com