Table 1 Key epidemiological data of patients related to their serological response to HPV16 antigens

Mean Age (yrs)

34.9

36.9

p = 0.460

34.8

36.0

p = 0.533

36.1

35.6

p = 0.805

Smoking status

%

Non-smoker (40)

92.5

7.5

OR = 2.8 (0.7–11.3);

72.5

17.5

OR = 1.4 (0.6–3.6);

85.0

15.0

OR = 3.7 (1.3–10.5);

p = 0.211

p = 0.495

p = 0.009

Current smoker (48)

81.3

18.7

64.6

35.4

60.4

39.6

N. cigarette/d

13.4

10.1

p = 0.285

13.8

10.9

p = 0.225

13.3

12.0

p = 0.603

Age start smoking (yrs)

18.9

19.6

p = 0.776

18.2

20.6

p = 0.122

19.5

18.1

p = 0.379

Years smoked

15.2

13.3

p = 0.592

16.5

12.0

p = 0.089

14.0

16.8

p = 0.296

¹ Contraception (%):

   Yes (53)

92.5

7.5

OR = 1.4 (0.3–6.8);

73.6

26.4

OR = 1.3 (0.5–3.4):

73.6

26.4

OR = 0.7 (0.2–2.1):

p = 0.694

p = 0.658

p = 0.560

   No (29)

89.7

10.3

69.0

31.0

79.3

20.7

^New partner (%):

   Yes (5)

100

-

OR = NC; p = 0.508

60.0

40.0

OR = 0.7 (0.2–2.2);

60.0

40.0

OR = 0.7 (0.2–2.1);

p = 0.630

p = 0.619

   No (76)

86.8

13.2

71.1

28.9

72.4

27.6

Sexually active (%):

   Yes (79)

89.9

10.1

OR = 5.9 (0.9–40.9);

70.9

29.1

OR = 1.6 (0.3–10.4);

74.7

25.3

OR = 4.4 (0.7–28.4);

p = 0.105

p = 0.631

p = 0.124

   No (5)

60.0

40.0

60.0

40.0

40.0

60.0

Partner HIV+ (%):

   Yes (8)

87.5

12.5

OR = 0.9 (0.1–8.7);

87.5

12.5

OR = 3.3 (0.4–28.3);

62.5

37.5

OR = 0.6 (0.1–2.8);

p = 1.000

p = 0.679

   No (75)

88.0

12.0

68.0

32.0

73.3

26.7

² Actual contraception

%

   Yes (37)

86.5

13.5

OR = 0.7 (0.2–2.7);

67.6

32.4

OR = 0.8 (0.3–2.1);

64.9

35.1

OR = 0.4 (0.1–1.1);

p = 0.726

p = 0.660

p = 0.093

   No (43)

90.7

9.3

72.1

27.9

81.4

18.6

² Condom Use

%

   Never (43)

90.7

9.3

72.1

27.9

72.1

27.9

   Often (14)

100

-

p = 0.138

78.6

21.4

p = 0.334

100

-

p = 0.022

   Always (18)

77.8

22.2

55.6

44.4

61.1

38.9

STD since last visit

%

   Yes (6)

100

-

OR = NC;

100

-

OR = NC;

83.3

16.7

OR = 1.7 (0.2–15.7)

p = 1.000

p = 0.175

   No (74)

89.2

10.8

68.9

31.1

74.3

25.7